Non-Keratinizing Squamous Cell Carcinoma from the Nasal Cavity Mimicking Palatal Salivary Gland Tumor: Case Report
이환규, 한다울, 김현민, 김동욱,
소속 상세정보
이환규 ( Lee Hwan-Gyu ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
한다울 ( Han Da-Wool ) - Yonsei University College of Dentistry Department of Oral Pathology
김현민 ( Kim Hyoun-Min ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
김동욱 ( Kim Dong-Wook ) - Yonsei University College of Dentistry Department of Oral and Maxillofacial Surgery
Abstract
Non-keratinizing squamous cell carcinoma (NKSCC) is a rare malignancy of the nose and paranasal sinuses which is characterized by a unique anastomosing ribbon-like growth pattern with absent of limited maturation and keratinization. NKSCC accounts for 10-27% of sinonasal squamous cell carcinomas and some of the NKSCCs are reported to be associated with high risk-HPV infection. Advanced lesion can involve the oral cavity with oral symptoms of palatal bulging, surface ulceration mimicking salivary gland tumors. Herein, we report a case of NKSCC of a 46-year old male, which clinically presented as a bulging mass on the mid palate and mimicked a palatal salivary gland tumor. We reviewed the clinical and histopathological considerations required for differential diagnosis of sinonasal carcinoma involving the oral cavity.
키워드
Non-keratinizing squamous cell carcinoma; Sinonasal carcinoma; Human papillomavirus; p16; Mucoepidermoid carcinoma
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